Coronary blood flow

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Coronary blood flow

per tissue mass of all human organs. The resting coronary blood flow is 250 ml min 1 (0.8 ml min 1 g 1 of heart muscle); this represents 5% of cardiac output. Ischaemia results when oxygen demand outstrips supply. Arterial oxygen extraction is 70–80%, compared with 25% for the rest of the body. Therefore, increased oxygen consumption must principally be met by an increase in coronary blood flow...

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Coronary Blood Flow

In the experimental animal the basic and controversial problem was studied of the influence of cardiac contraction on coronary blood flow. Normally beating hearts were perfused at a constant pressure, and coronary inflow and outflow were determined. In order to assess the role of systole, prolonged periods of ventricular asystole and fibrillation were induced and observations were made of the c...

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Coronary Collateral Blood Flow

Background. Although aspirin exerts beneficial antiplatelet activity in patients with coronary artery disease, cyclooxygenase blockade produced by aspirin causes a potentially deleterious effect by interrupting endothelial production of prostacyclin. Collateral vessels that develop in response to coronary occlusion display prominent endothelial cell proliferation and undergo vasoconstriction in...

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Coronary Blood Flow

Background Although neurostimulation has been shown to be of benefit in angina pectoris, the exact mechanism of its action is not clear. This study was performed to examine the effect of transcutaneous electrical nerve stimulation on coronary blood flow. Methods and Results The effect of transcutaneous electrical nerve stimulation was studied in 34 syndrome X patients (group 1), 15 coronary art...

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Coronary Blood Flow

Assessment of coronary blood flow and the vasodilator reserve capacity of individual coronary arteries in the catheterization laboratory has been hampered by methodologic limitations. We have developed and validated a small Doppler catheter that can subselectively measure phasic coronary blood flow velocity (CBFV). In seven anesthetized calves, CBFV was varied from 0.1 to 5.7 times control CBFV...

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ژورنال

عنوان ژورنال: Continuing Education in Anaesthesia Critical Care & Pain

سال: 2005

ISSN: 1743-1816

DOI: 10.1093/bjaceaccp/mki012